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High-confidence example
Abstract Purpose To investigate knee flexion strength symmetry across four different strength tests in patients who underwent anterior cruciate ligament (ACL) reconstruction (ACLR) using hamstring tendon (HT) autograft. Methods Data were collected between June 2024 and August 2025. Patients who underwent ACLR with HT autograft and performed (a) seated isokinetic concentric knee flexion (Biodex), (b) Nordic hamstring exercise (NordBord), (c) prone isometric 90° knee flexion with dorsiflexion (ISO90 DF) and (d) plantar flexion (ISO90 PF) ≥ 4 months after ACLR were included. The primary analysis was the cross‐sectional pairwise comparison of limb symmetry index (LSI) using a paired‐samples t test. The secondary analysis compared the proportion of patients achieving an LSI ≥ 90% in each testing modality using McNemar's test. Comparisons with a control group consisting of patients with patellar tendon and quadriceps tendon autografts were performed using an independent‐samples t test and Fisher's exact test, respectively. Statistical significance was set at p < 0.05. Results A total of 101 patients were included, including a control group ( n = 33). Patients with HT autograft had a mean age of 25 ± 8 years, with the most common follow‐up time being 12 months. Knee flexion strength in the Biodex displayed the LSI closest to symmetry (98.4%). The mean difference was 43.9% ± 16.7% (95% confidence interval [CI] [39.9; 47.8%], p < 0.001, d = 2.62 95% CI [2.1; 3.1]) compared to the LSI of the prone ISO90 PF. Fifty‐seven (80%) patients passed the ≥90% cut‐off in LSI for the Biodex test, while only 2 (3%) patients passed the prone ISO90 PF. The HT autograft group demonstrated lower LSI with the NordBord, ISO90 DF and ISO90 PF ( Δ = −12.2 to −37.4%, p = 0.001 to <0.001) compared with the control group. Conclusions Knee flexion strength LSI varied substantially across the four test modalities in patients with HT autograft, highlighting the need to consider the hip, knee and ankle positions when evaluating knee flexion strength recovery after ACLR in patients with HT autograft. Level of Evidence Level II, prospective comparative study.
matched text: “knee flexion”
Low-confidence example
Background: A common musculoskeletal issue that can affect dynamic knee stability, balance functional performance and quality of life is chronic knee pain. Exercise therapy is a first-line treatment, but it’s unclear if Biceps Femoris-focused eccentric exercise has any additional benefits. Objective: To compare the effects of Biceps Femoris–focused eccentric exercise and regular physiotherapy on dynamic knee stability and pain in patients with chronic knee pain. Methods: This was a parallel group, single-blinded, randomized controlled trial conducted in the outpatient physiotherapy department of JPMC, BAWS Health Facility, Karachi, Pakistan, from 01 March 2026 to 31 August 2026. A total of 160 participants with chronic knee pain were randomly assigned to either the Biceps Femoris–focused eccentric exercise group (n = 80) or the standard physiotherapy exercise group (n = 80). For 6 weeks, both groups underwent 3 sessions of supervised exercise therapy three times per week for six weeks (18 sessions total). Progressive eccentric hamstring exercises emphasizing eccentric knee flexion, external tibial rotation and single-leg control were performed by the Biceps Femoris-focused eccentric exercise group. These exercises included Romanian deadlifts, lateral step-downs with external rotation cueing, prone knee curls with external tibial rotation, side-lying hip extension with knee flexed 30-45°, standing hip hinges with band resistance, single-leg squats to a box. Straight leg raises, mini-squats (0–45°), step-ups, terminal knee extension with band, static hamstring and calf stretches, and single-leg stance balance training were among the traditional knee rehabilitation exercises performed by the standard physiotherapy group. A total of 149 participants finished the study and were included in the final analysis (74 in the Biceps Femoris–focused eccentric exercise group and 75 in the standard physiotherapy group). The primary outcomes were dynamic knee stability which was assessed using the Star Excursion Balance Test, and pain intensity was assessed by using the Numerical Pain Rating Scale. Secondary outcomes were functional performance, knee-related disability, and adverse events. Data were analyzed using SPSS version 26.0, with statistical significance set at p < 0.05. Results: Dynamic knee stability, pain, functional performance and knee related disability all improved in both groups after six weeks. But compared to the standard physiotherapy group, the Biceps Femoris-focused eccentric exercise group significantly improved dynamic knee stability (mean change: 8.4 ± 3.1 vs. 3.6 ± 2.7; mean difference: 4.8; 95% CI: 3.9 to 5.7; p < 0.001). Additionally, the eccentric exercise group experienced a significantly higher reduction in pain (mean change: 3.3 ± 1.2 vs. 2.1 ± 1.3; mean difference: 1.2; 95% CI: 0.8 to 1.6; p < 0.001). Functional performance and knee related disability improved more in eccentric exercise group. The most frequent adverse event was mild muscle soreness; no significant adverse events were noted. Conclusion: For patients with chronic knee pain, Biceps Femoris-focused eccentric exercise was more beneficial than conventional physiotherapy in terms of enhancing dynamic knee stability and lowering pain. It might be suggested as a practical and safe supplement to conventional physiotherapy rehabilitation.
matched text: “knee flexion”
Matched source items · 9 in window
exact abstract match · confidence 0.79 · authority 1.00 · matched “knee flexion”
exact title match · confidence 0.75 · authority 0.15 · matched “knee flexion”
exact abstract match · confidence 0.74 · authority 1.00 · matched “knee flexion”
exact title match · confidence 0.84 · authority 0.75 · matched “knee flexion”
exact abstract match · confidence 0.74 · authority 1.00 · matched “knee flexion”
exact title match · confidence 0.94 · authority 1.00 · matched “knee flexion”
exact abstract match · confidence 0.74 · authority 1.00 · matched “knee flexion”
exact abstract match · confidence 0.74 · authority 1.00 · matched “knee flexion”
exact abstract match · confidence 0.74 · authority 1.00 · matched “knee flexion”